You can obfuscate what the information is and/or encrypt what is in the files, but be aware that all these do is slow determined players down. If someone really wants to take apart the file, they will. I've played more than one game where someone had figured out how to take a hex editor in and adjust save games or other files. Ultimately, if you're worried about the data, what you're shooting for is making it not easy.
Just keep in mind that you have to balance that protection with both how much effort the game has to put in for encrypting and decrypting the data, plus the risk of data being corrupted when it is put in or taken out of the file.
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